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The Honolulu Advertiser
Posted on: Sunday, July 15, 2007

Study hints at 2 paths leading kids to autism

By Anita Manning
USA Today

BEHAVIORS TO LOOK FOR

No single behavior is enough to diagnose autism, researchers say, but here are some signs to watch:

  • Lack of gesturing, vocalizing and eye contact.

  • An inability to pick up cues from watching facial expressions.

  • Unusual play patterns. A typical child given a toy fork will pretend to eat with it. A child with autism may repeatedly tap it on the table or pick it up and drop it.

  • Fewer words, gestures and sounds than typically developing children.

    Source: Kennedy Krieger Institute

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    Children with autism can be identified as early as 14 months old, the youngest age at which the disorder has been diagnosed, a study by researchers at the Kennedy Krieger Institute in Baltimore suggests.

    But about half the time, symptoms may not show up until months later. That suggests at least two distinct paths leading to autism: one that starts early in life and one in which a child seems to develop normally and then regresses, losing language and social skills.

    Results of the study, the first to follow toddlers from 14 months until they turn 3, could allow earlier treatment to reduce the effects of autism, says Rebecca Landa, lead author of the report published in the Archives of General Psychiatry.

    The range of developmental impairments known as autism spectrum disorders, or ASD, is marked by an inability to communicate and interact with others. Its cause is not known, but most researchers believe genetic factors play a role.

    Most studies have relied on interviews with parents and examinations of family videos to look for early signals, such as a child's lack of response to his name or failure to engage with others.

    Scientists know that "we can reliably diagnose autism at age 2, but only by real experts," Landa says. "What's different about this is we can show that we can stretch that down close to the first birthday, but the caveat is we can't do it for all children."

    The study involved 107 children who were considered at high risk for autism because they had a sibling with the disorder and 18 low-risk children who had no family history of autism.

    Behavior differences in those with and without ASD at 14 months can be seen in videos that show toddlers interacting with a researcher. In one, a normally developing boy reacts happily when given a toy penguin, gives it to the researcher and laughs when she hands it back. "He integrates looking, giving and smiling," Landa says. "That is what I call the package, and the package is very seldom seen at 14 months of age in kids who have ASD."

    Landa cautions parents not to be overly alarmed if a child occasionally exhibits a worrisome trait. Autism involves many developmental disruptions that continue over time. "I don't know any children who don't do weird things" now and then, she says. "If it's going to be ASD, it's going to stick."