FOXBOROUGH, Mass. — Tom Brady threw for 279 yards and three touchdowns and got three TDs from players picked up last spring: Randy Moss with two receptions, and Adalius Thomas with a 65-yard interception return.

The victory came three days after the NFL fined Patriots coach Bill Belichick $500,000, the team another $250,000 and took away what is almost sure to be a first-round draft choice, all for spying.

Moss had eight receptions for 105 yards and 23 and 24-yard TD catches. Wes Welker had eight catches for 91 yards.

The Patriots are 2-0, the Chargers 1-1.

Browns 51, Bengals 45

CLEVELAND — Derek Anderson threw five touchdown passes, Jamal Lewis rushed for 216 yards and the Cleveland Browns, so desperate after losing their home opener they traded their starting quarterback, outlasted the Cincinnati Bengals and Carson Palmer 51-45.

Anderson had a breakout game against the Browns (1-1), going 20-of-33 for 328 yards and the five TDs, which tied a team record shared by Frank Ryan, Bill Nelsen, Brian Sipe and Kelly Holcomb.

A week ago, Anderson was backing up Charlie Frye before being brought in during the first half. Two days later, the Browns dealt Frye to Seattle.

Palmer went 33-of-50 for 401 yards and tossed a career-high six TDs, but his final chance to rally the Bengals (1-1) ended when he was intercepted with 21 seconds left by Leigh Bodden, who made a diving grab near Cleveland's sideline.

It was just the third time in NFL history that two QBs threw five TD passes in the same game. Oakland's Tom Flores (6) and Houston's George Blanda (5) both did it on Dec. 22, 1963, and Billy Kilmer of New Orleans (6) and Charley Johnson of St. Louis (6) also did on Nov, 5, 1969.

Johnson had 11 catches for 209 yards and two TDs, and jumped headfirst after the second score into the Dawg Pound, where he was baptized in a shower of beer by Cleveland's rowdiest fans.

Packers 35, Giants 13

EAST RUTHERFORD, N.J. — Brett Favre picked a near-perfect way to become the winningest quarterback in NFL history.

Favre completed his first 14 passes of the second half and threw three touchdown passes to rally the Green Bay Packers over Eli Manning and the New York Giants. The victory was the 149th of Favre's 17-year career, giving him one more win than Hall of Famer John Elway.

It also gave the Packers their first 2-0 start since they won their first three in 2001.

The loss was the second straight for the undisciplined and error-prone Giants, something that hasn't happened at the start of a season since 1996.

Favre was 29-of-38 for 286 yards, including 18-of-21 for 147 yards in the second half. Rookie DeShawn Wynn added touchdown runs of 6 and 38 yards.

Manning, whose playing status was uncertain all week because of a sprained shoulder, was 16-of-29 for 211 yards and a touchdown.

Texans 34, Panthers 21

CHARLOTTE, N.C. — With Matt Schaub throwing for 227 yards and two touchdowns and backed up by an effective running game, the Houston Texans forced three turnovers and recovered from a sluggish start to go 2-0 for the first time in franchise history.

Houston went 24-56 in its first five years with David Carr, who was released in the offseason when the Texans traded for Schaub. Carr, now the Panthers backup, could only watch as Andre Johnson caught seven passes for 120 yards and two scores, Ahman Green rushed for 71 yards and a TD and the Texans rallied from a 14-0 deficit. They handed the Panthers (1-1) their fourth consecutive loss in their home opener.

The Panthers' Steve Smith, who caught eight passes for 153 yards and three TDs, had little help. Jake Delhomme threw for 307 yards, but had an interception. DeShaun Foster lost a fumble.

Colts 22, Titans 20

NASHVILLE, Tenn. — Peyton Manning threw for 312 yards and a touchdown, and the Indianapolis Colts held off Tennessee when their defense stopped Vince Young on a final-drive comeback.

Unlike last December, when Rob Bironas capped a similar comeback with a 60-yard field goal, the Colts collapsed around Young on fourth-and-4. That forced him to lob the ball away in the final seconds.

Manning, 28-of-42, kneeled down to run out the final seconds as champion Indianapolis (2-0) reminded Tennessee (1-1) which team remains atop the AFC South.

Adam Vinatieri had one of his worst days in years despite making field goals of 22, 39 and 20 yards. He had an extra point blocked and a field goal partially blocked that bounced off the crossbar before going over. He also missed a 36-yarder.

Young was 17-of-27 for 184 yards and a touchdown, but couldn't lead the Titans to 2-0 for the first time since 1999.<

49ers 17, Rams 16

ST. LOUIS — Dante Hall fumbled while catching a punt and Marcus Hudson recovered for San Francisco, setting up the winning field goal by Joe Nedney.

The Rams' Jeff Wilkins missed a 56-yard field goal try with 59 seconds to play, the ball falling about a yard short of the goal post.

The 49ers (2-0) won despite struggling offensively most of the game. St. Louis (0-2) had 392 total yards to 186 for San Francisco. Alex Smith was 11-for-17 for 126 yards. Frank Gore scored two touchdowns and gained 81 yards on 20 carries.

Marc Bulger was 24-for-41 for 368 yards and one touchdown. Isaac Bruce caught eight passes for 145 yards. Rams running back Steven Jackson gained 60 yards on 21 carries.

Buccaneers 31, Saints 14

TAMPA, Fla. — Joey Galloway caught four passes for 135 yards and two touchdowns, tormenting the Saints for the sixth straight game between the NFC South rivals and leading the Buccaneers to a victory.

The Saints (0-2) were embarrassed for the second consecutive week and have been outscored 72-24 after having one of the NFL's most explosive offenses and reaching the NFC championship game last season.

Jeff Garcia completed 10 of 16 passes for 243 yards and no interceptions for the Bucs (1-1).

Drew Brees was 26-of-44 for 260 yards with one touchdown for the Saints, but never got into a rhythm.

Steelers 26, Bills 3

PITTSBURGH — Willie Parker ran for a touchdown and 126 yards, and Ben Roethlisberger threw for a score as the Pittsburgh Steelers controlled the clock and the tempo while pulling away from Buffalo.

It was the Bills' first game since tight end Kevin Everett badly injured his spinal cord.

Buffalo's J.P. Losman couldn't generate any offense as the Bills (0-2) were outgained 421-223. The Steelers, whose first four scores came on field goals by Jeff Reed, finally took control with the game's only two touchdowns in the final quarter and a half.

Mike Tomlin won his home opener as Steelers' coach, just as Bill Cowher (1992) and Chuck Noll (1969) did before him. Tomlin also matched Cowher by winning his first two games. The Bills, with Everett believed to be watching from his hospital room, lost their fourth in a row counting their final two of last season.

Jaguars 13, Falcons 7

JACKSONVILLE, Fla. — The Jaguars sacked Joey Harrington seven times and held the Atlanta Falcons under 100 yards rushing.

Atlanta's biggest problem came on special teams, where rookie Matt Prater missed two field goals. His second miss Sunday would have given the Falcons (0-2) a 10-3 advantage. Instead, David Garrard drove Jacksonville (1-1) on consecutive scoring drives to put the team ahead for good.

Garrard was 17-of-25 for 272 yards, including a 14-yard touchdown pass to Reggie Williams. Harrington finished 12-of-20 for 200 yards.

Broncos 23, Raiders 20, OT

DENVER — Jason Elam's 23-yard field goal with 5:48 left in overtime gave the Broncos a win just minutes after the Raiders had been celebrating what they thought was their own wild win.

Sebastian Janikowski nailed a 52-yard field goal at 11:13 of overtime. But as the Raiders rushed the field in celebration and the Broncos (2-0) hung their heads in defeat, the officials ruled Denver called a timeout just before the snap. On the retry, Janikowski's kick hit the left upright, giving the Broncos new life and the ball at their 42.

They drove to the Oakland 6 and Elam nailed it on first down — and the Raiders (0-2) didn't bother calling their own timeout.

Oakland's LaMont Jordan gained a career-best 159 yards on 25 carries.

Bears 20, Chiefs 10

CHICAGO — Devin Hester scored on a 73-yard punt in the second quarter and set up a field goal in the third with another long return for the defending NFC champions.

Cedric Benson carried 24 times for 101 yards, eight shy of his career high for the Bears (1-1). Rex Grossman was 20-for-34 with 160 yards and a touchdown, but was picked off twice after passing for 145 yards against the Chargers.

Minutes after blocking a 48-yard field goal by Dave Rayner, the Bears came up big again against the Chiefs (0-2). With the ball on the 16, Charles Tillman deflected a pass intended for Sammie Parker in the end zone and Danieal Manning intercepted. The Bears hung on from there.

Ravens 20, Jets 13

BALTIMORE — Kyle Boller threw for 185 yards and two touchdowns, and the Baltimore Ravens overcame a late charge by Kellen Clemens and the New York Jets in a matchup of backup quarterbacks.

Making his first NFL start, Clemens cut a 20-3 deficit to seven points in the fourth quarter and took the Jets (0-2) to the Baltimore 7 before Ray Lewis intercepted a deflected pass in the end zone with 1:04 left to preserve the win.

Clemens replaced Chad Pennington, who injured his right ankle in the opener against New England. He threw two interceptions but went 19-for-37 for 260 yards — 176 of them in the fourth quarter.

Boller played in place of Steve McNair, who hurt his groin in Baltimore's season-opening loss to Cincinnati, and went 23-for-35 with two touchdowns for the Ravens (1-1).

Cowboys 37, Dolphins 20

MIAMI — After winning a shootout in the season opener, Dallas took advantage of five takeaways and a ball-control offense to beat the hapless Miami Dolphins.

The Cowboys intercepted Trent Green four times and recovered a fumbled snap. Green also fumbled attempting a spike play late in the first half, possibly costing Miami points.

Dallas came from behind twice and nursed a 20-13 lead early in the fourth quarter, then sealed the win with two touchdowns in the final 4:01. Anthony Henry had two interceptions, and Ken Hamlin and Roy Williams made one apiece as the Cowboys improved to 2-0 under new coach Wade Phillips.

Arizona 23, Seattle 20

GLENDALE, Ariz. — After blowing a 17-0 lead in what looked like another classic Arizona collapse, Darnell Dockett recovered a fumble by Seattle's Matt Hasselbeck. Then, Neil Rackers kicked a 41-yard field goal with 1 second to go, giving the Cardinals the victory over the Seahawks.

Rackers' 52-yarder tied it at 20 with 4:44 to play.

The Seahawks (1-1) took the subsequent kickoff and drove toward what could have been the winning score.

On first-and-5 from the Arizona 36, linebacker Gerald Hayes disrupted an already botched handoff from Hasselbeck to Shaun Alexander. The ball popped free, and Dockett recovered at the Seattle 45 with 1:48 to go. Edgerrin James, who rushed for 123 yards and a touchdown in 23 carries, carried four times before Arizona (1-1) called timeout to take the winning kick.

Lions 20, Vikings 17, OT

DETROIT — Jason Hanson's 37-yard field goal in overtime lifted Detroit over Minnesota and ended a 10-game losing streak in the series.

The Lions and Vikings combined for nine turnovers in regulation — and two missed field goal attempts in the final 35 seconds.

The 10th turnover — Brooks Bollinger's fumbled snap — gave Detroit the ball at the 50. Jon Kitna, who missed about two quarters after being shaken up, ran the ball twice to pick up a key first down, and Brian Calhoun's 17-yard run set up Hanson's kick.

Detroit (2-0) has won its opening two games for the first time in three years.