What's the most important nation in the Middle East right now?

Is it Saudi Arabia, with the world's largest oil reserves? Is it Israel, one of the region's only democracies? Is it Egypt, long the political power broker?

No, the most important nation in the Middle East is Syria, a poor nation with few natural resources and a second-generation dictator who has the nation locked down so tight that Syrians are afraid even to talk.

For all of that, no other nation is so strategically located. No other state has the power to wreak so much havoc in the region — or, potentially to bring such positive change — which is certainly why the Obama administration is trying so hard to make friends.

Late last month, George Mitchell, the administration's Middle East envoy, told Syrian President Bashar Assad that the United States would increase military ties and ease sanctions, in place since 2003. In the spring the State Department said it would return an ambassador to Damascus for the first time in four years.

Why Syria? Consider its neighbors: Israel, Lebanon, Turkey, Iraq and Jordan. The Iranian border is just a short distance away. In that spot, oh what mischief Syria can (and does) make. Iran is Syria's ally and patron, and Assad helps the mullahs in Tehran deliver arms and money to Islamic Jihad fighters in the West Bank and Hamas militants in Gaza. In fact, Hamas' supreme leader, Khaled Meshal, lives in Damascus.

With Iranian help, Syria arms and equips Hezbollah, another militant group in southern Lebanon. Hezbollah is an enemy of Israel — and the democratic government in Beirut. The American military continues to complain that Syria offers safe haven to foreign militants who cause trouble in Iraq, as U.S. troops begin to withdraw.

Syria may hold the key to Middle East. If Assad and Benjamin Netanyahu, Israel's prime minister, could negotiate a return of the Golan Heights and a peace treaty between the two states, the other dilemmas facing Israel might more easily be resolved.

As if that were not enough, Syria is the only nation in the Middle East that worked with North Korea to create a nuclear reactor, apparently in search of a nuclear weapon to match Israel's. Israel bombed the site in 2007.

So shouldn't we wish Obama luck? Is there a better candidate for improved relations? No. Is there any realistic chance that the United States can peel Syria away from Iran and Arab extremists? Probably not.

First, consider what Assad would face if he abandoned Iran and the extremists. No more under-the-table foreign aid from Iran. Assad would have to rely on Washington. Syria has no friends on Capitol Hill, and grudges there last lifetimes.

To keep aid coming, Syria would have to take seriously the three major reports that come out of the State Department each year and clean up its act. It has a long way to go. The most recent human rights report says: "The government systematically repressed citizens' abilities to change their government. In a climate of impunity, there were instances of arbitrary or unlawful deprivation of life. Members of the security forces tortured and physically abused prisoners and detainees."

The department's human trafficking report places Syria in Tier III, the worst classification.

But Assad has an even more important reason for treating Washington cautiously: his own political survival. His family and much of the ruling regime in Damascus is Allawite, a Shiite Muslim sect. The majority of Syria is Sunni. To survive Assad must maintain a strong strategic relationship with Iran, the capital of Shiite Islam.

President Obama, want to make friends with Syria, the region's most important player right now? Best of luck.