IRVINE, Calif. — Brandon Meredith hit two home runs and Tyler Lavigne pitched into the eighth inning as San Diego State eliminated defending College World Series champion Fresno State with a 4-1 victory in an NCAA baseball regional game tonight.

Coach Tony Gwynn's Aztecs (41-22) will face the loser of the UC Irvine-Virginia matchup in an elimination game Sunday.

Fresno State's defense of its national title ended in two regional losses as Lavigne limited the Bulldogs (32-30) to just five hits and an unearned run in 7 1-3 innings while striking out eight and walking one. Addison Reed got four outs for his 20th save.

Kenny Wise accounted for Fresno's only run with a fourth-inning triple that scored Brennan Gowens.