SAN DIEGO — The boos and rude chants came thundering down on Eli Manning from the moment he ran onto the field, rising up every time he lined up under center.

San Diegans got their payback, and it was raucous.

"I knew it was going to be loud," said Manning, who spurned the Chargers 17 months ago, then lost to them as San Diego defeated the New York Giants 45-23 last night.

While the sellout crowd of 65,373 delighted in tormenting Manning, it also exhorted the Chargers and LaDainian Tomlinson, who ran for 192 yards and three touchdowns, and threw for another score on a night that left thousands of ear drums ringing, especially Manning's.

Drew Brees threw two touchdowns for the Chargers (1-2), who had 485 total yards. Manning threw for a career-high 352 yards and two touchdowns for the Giants (2-1), who gained 424 yards.

A few days before the 2004 draft, Manning's camp told the Chargers to take someone else with the No. 1 pick, and implied the Ole Miss star would sit out if San Diego selected him.

General manager A.J. Smith took Manning anyway, then traded him to the Giants for quarterback Philip Rivers — taken at No. 4 — and a handful of picks.

Fans brought signs such as "Hey Eli, Nobody Likes You," "Drew's Your Daddy," and "Daddy's Little Girl," a shot at Manning and his father, Archie.

"I saw my name on a few things," Manning said. "I'm sure they made a good profit on T-shirts and things."

BENGALS 24, BEARS 7

CHICAGO — Cincinnati, which entered the game with a league-leading 10 takeaways, picked off Chicago quarterback Kyle Orton five times and became the first NFL team in 34 years to intercept five passes in consecutive games.

Madieu Williams, Keiwan Ratliff, Tory James, Deltha O'Neal and Brian Simmons each intercepted Orton. The Bengals (3-0) intercepted Minnesota's Daunte Culpepper five times in last week. The 1971 Cleveland Browns were the last to pick off five in consecutive games.

Chicago is 1-2.

EAGLES 23, RAIDERS 20

PHILADELPHIA — David Akers, fighting through a strained right hamstring, kicked a 23-yard field goal with 9 seconds left for Philadelphia.

Donovan McNabb, playing with chest and groin injuries, threw for 365 yards and two touchdowns for the Eagles (2-1). Terrell Owens had nine catches, including his 100th career touchdown.

Oakland is 0-3.

ATLANTA 24, BUFFALO 16

ORCHARD PARK, N.Y. — Shaking off a tender hamstring he hurt last weekend, Atlanta's Michael Vick threw two touchdown passes and scrambled for 64 yards on nine carries.

Warrick Dunn rushed for 97 yards and T.J. Duckett added 75 yards rushing and a touchdown for the Falcons (2-1).

Willis McGahee led Buffalo (1-2) with 140 yards rushing and a touchdown. Linebacker Takeo Spikes hurt his right Achilles' tendon in the second quarter and did not return.

RAMS 31, TITANS 27

ST. LOUIS — Marc Bulger threw three touchdown passes and St. Louis (2-1) hung on for a turnover-filled victory. The Titans (1-2) converted three turnovers into 17 points while the Rams got an 85-yard interception return from Adam Archuleta for a touchdown.

Torry Holt caught nine passes for 163 yards in the first three quarters and Kevin Curtis' 10-yard catch on the first play of the fourth quarter was the go-ahead score for the Rams.

DOLPHINS 27, PANTHERS 24

MIAMI — Lance Schulters intercepted Jake Delhomme with 2 minutes left to set up Olindo Mare's game-winning field goal.

Carolina's Steve Smith had 11 catches for 170 yards and three touchdowns. His 53-yard score midway through the fourth quarter tied the score at 24.

Miami is 2-1. Carolina is 1-2.