FRESNO, Calif. — Vai Taua ran for a career-best 263 yards and a late touchdown, and quarterback Colin Kaepernick added 118 yards and two scores in Nevada's 472-yard rushing attack in a 41-28 victory over Fresno State tonight.

Courtney Randall had 66 yards rushing and another touchdown for the Wolf Pack (5-4, 3-2 WAC), who rarely stopped moving forward in another prodigious performance by Kaepernick and their unique-looking "pistol" offense.

They finished with 600 total yards — their third 600-yard game this season — in Nevada's first victory in Fresno since 1998.

Seyi Ajirotutu caught two touchdown passes from Tom Brandstater for the Bulldogs (5-4, 2-3), who lost their second straight and dropped to 1-3 at Bulldog Stadium this season with just their second loss to Nevada in the schools' last 10 meetings. Brandstater went 23-of-43 for 260 yards, but threw two interceptions.

A.J. Jefferson returned a kickoff 93 yards for a score in the fourth quarter to keep Fresno State close, but Kevin Grimes intercepted Brandstater's fourth-down pass in the final minutes, and Ajirotutu fumbled at the Nevada 10 with 1:57 to play.

Lonyae Miller also rushed for a score, but Fresno State simply couldn't stop the Wolf Pack, who got Kaepernick's third 100-yard rushing game and Taua's first 200-yard performance of the season. Mike McCoy caught an early touchdown pass, and Taua — a third-stringer when the season began — had the sixth-highest rushing total in school history while averaging 9.4 yards per carry.

Kaepernick and Brandstater both grew up in Turlock, Calif., a San Joaquin Valley town about 80 miles north of Fresno, graduating from different high schools two years apart. While Brandstater is a more classic dropback passer, the 6-foot-6 Kaepernick is thriving in the pistol, a shotgun derivative which involves plenty of option rushing and multiple-receiver sets.

Nevada converted a fourth-and-10 on its opening drive, which ended in a 16-yard TD run up the middle by Kaepernick. The quarterback then hit McCoy on the Fresno State sideline on a fourth-and-6 play for a 36-yard score early in the second quarter.

The Wolf Pack racked up 330 yards of offense and made three lengthy scoring drives in the first half, but Nevada also missed a golden opportunity to score more points in the final seconds.

Taua was stopped at the Fresno State 1, and the clock ran out before the Wolf Pack could call a timeout. The officials didn't see Nevada coach Chris Ault, who won his 196th game, frantically signaling to stop the game before the half ended.

Miller turned the corner on Nevada's defense midway through the third quarter for a 34-yard TD run, but Kaepernick capped another lengthy drive with a 2-yard scoring dive. Kaepernick's 20th rushing score tied him with Hall of Famer Marion Motley for ninth place in the school's career touchdowns list.

Fresno State pulled to 31-21 on the third quarter's final play when Ajirotutu made his second TD catch, but Taua capped a 12-play drive with a 25-yard run for a score with 8:40 to play. After Grimes' interception, Brett Jaekle made his second field goal.