COLLEGE STATION, Texas — Sam Bradford threw touchdown passes to four different receivers, Chris Brown ran for three scores and No. 6 Oklahoma started fast again and routed Texas A&M 66-28 today.

DeMarco Murray, Matt Clapp, Ryan Broyles and Juaquin Iglesias had TD catches and Bradford had a touchdown run for the Sooners (9-1, 5-1 Big 12), who set a single-game scoring record for an opponent at Kyle Field.

The Sooners have scored 231 points in four games since a 45-35 loss to Texas. Their defense was equally impressive in this one, holding the Aggies (4-6, 2-4) to 26 rushing yards and forcing four turnovers.

Cyrus Gray scored on a 98-yard kickoff return for a touchdown and set an A&M record with 261 kick return yards. But receiving lots of kickoffs was bad news for the Aggies, who were held to 278 total yards and dropped to 2-5 at home this season.

The Sooners have always struggled at Kyle Field and an unranked A&M team beat No. 1 Oklahoma 30-26 here in 2002. But Oklahoma had no problems in this one, leading 38-14 at halftime and 66-21 after three quarters.

Bradford completed 22 of 33 passes for 320 yards and tied a school record with his eighth 300-yard game of the season. Murray rushed for 123 yards and Brown ran for 117 against the Big 12's second-worst rushing defense.

Oklahoma outscored its first nine opponents 180-27 in the first quarter and needed only 90 seconds to score on the Aggies.

Murray broke a 70-yard run on the Sooners' second play from scrimmage and Bradford scrambled for a 15-yard touchdown with 13:31 left in the quarter. Oklahoma scored on its first possession for the ninth time in 10 games.

The Aggies went three-and-out on their first series and Murray caught Bradford's 35th touchdown pass of the season with 8:05 left in the first quarter.

On Oklahoma's next series, Bradford found Jermaine Gresham for a 23-yard gain to the A&M 22 and Brown scored with 5:44 remaining in the quarter. The 49-second possession was Oklahoma's 13th touchdown drive this season that lasted under a minute.

The Sooners outgained A&M 238-13 in the quarter. A&M coach Mike Sherman gathered his team for a fiery pep talk before the second quarter began, but it didn't make a difference — Bradford threw a 28-yard TD pass to Clapp with 14:27 left in the half to make it 28-0.

Gray returned the ensuing kickoff 67 yards to set up Jerrod Johnson's 20-yard touchdown pass to Jamie McCoy.

Johnson dived into the end zone with 5:11 left in the half to cut Oklahoma's lead to 28-14.

The Aggies were barely stemming the tide.

Broyles took a short pass from Bradford, evaded five A&M defenders and got to the 5, setting up another touchdown for Brown. Oklahoma got the ball back with 34 seconds left and Stevens kicked a 42-yard field goal on the second-to-last play of the half.

The Sooners had 423 yards and 18 first downs in the half, while the Aggies had minus-11 yards rushing and went 2-of-10 on third downs.

Johnson threw his first interception in 213 attempts, tying the Big 12 record, in the third quarter when Oklahoma linebacker Keenan Clayton picked off a pass.

Brown's 28-yard TD run with 8:39 left in the third quarter pushed Oklahoma over 50 points for the sixth time this season. The Sooners topped 500 yards for the seventh time this year.

Joey Halzle replaced Bradford early in the fourth quarter.

Stephen McGee replaced Johnson with 6:23 left in the third quarter. McGee, a senior, won the starting quarterback job in the fall, but he's missed all but one play in the last five games with a shoulder injury.