MIAMI — Josh Johnson lost his no-hit bid in the sixth inning, shortly after a heckling New York Mets fan made him laugh. Things became more serious when he lost his shutout with two outs in the ninth.

But he was determined not to lose the game.

Johnson persevered through a shaky finish to close out a five-hitter yesterday, and the Florida Marlins scored two unearned runs to hand Johan Santana his first loss since June 28 by beating the Mets, 2-1.

"I said before the game I was going to go eight or nine innings," said Johnson, as the Marlins won two of three from the Mets. "I finished what I started out to do. That's huge for me."

While Johnson pitched his second complete game in 45 career starts, Santana was just as good, allowing only three hits in seven innings and striking out 13. But left fielder Daniel Murphy dropped a fly ball in the second inning for an error that led to both Florida runs.

Santana (1-1) had made 18 starts in a row without a loss, winning 10 consecutive decisions.

"It's just one mistake that he made that cost us the whole ballgame," Santana said. "It was a fun game. Johnson did a great job, I was trying to do mine, and at the end he won."

Johnson (2-0) was on deck to bat in the fifth when a fan attempting to jinx him began hollering about his no-hitter.

"I just started laughing," Johnson said. "I'm sure it was a Mets person."

Luis Castillo ended the no-hit bid the next inning with a broken-bat single.

Johnson was one strike from a three-hit shutout when Carlos Delgado doubled. Carlos Beltran followed with an RBI single before Ryan Church's soft liner was caught by left fielder Brett Carroll, who made a backhanded, game-ending grab at the shoetops.

REDS 2, PIRATES 0:

Aaron Harang threw a three-hitter, Brandon Phillips hit a two-run homer and host Cincinnati overcame a triple play by Pittsburgh to split a two-game series. Harang (1-1) faced just three batters over the minimum while pitching his sixth shutout and 12th complete game.

CARDINALS 3, ASTROS 0:

Kyle Lohse (2-0) threw a career-best three-hitter, retiring 24 in a row after giving up a single on his first pitch, and host St. Louis completed a three-game sweep of Houston. Khalil Greene had three hits and an RBI, and Ryan Ludwick extended his hitting streak to 16 games with an RBI single for the Cardinals.

PADRES 6, GIANTS 1:

Chris Young (2-0) allowed four hits and an unearned run in seven innings, and Nick Hundley had a career-high four hits as host San Diego completed a three-game sweep of San Francisco. Tim Lincecum (0-2), the reigning NL Cy Young Award winner, gave up four runs and a career-high 10 hits over 5 1/3 innings.

DODGERS 3, DIAMONDBACKS 1:

Randy Wolf tossed two-hit ball into the eighth inning as Los Angeles won two of three against host Arizona. Wolf (1-1) allowed one run, struck out five and walked two in seven-plus innings.

BRAVES 8, NATIONALS 5:

Chipper Jones drove in two runs, including a tiebreaking RBI single, and host Atlanta handed Washington its sixth straight loss to start the season. Jair Jurrjens (2-0) gave up five hits and walked five in 5 1/3 innings but allowed only four runs, three earned.

PHILLIES 7, ROCKIES 5:

Pinch-hitter Matt Stairs connected for a tiebreaking two-run homer in the ninth inning as Philadelphia won the last two of the three-game series at Colorado. Chase Utley tied it at 5 with a two-run homer in the eighth and Ryan Howard had three hits for the Phillies.

CUBS 8, BREWERS 5:

Alfonso Soriano smacked the first pitch of the game off the facade in center field for a home run to lead visiting Chicago over Milwaukee. The Cubs took two of three games from their NL Central rivals — and didn't even break a sweat as they retook the lead when Milwaukee pitchers walked home four runs in a miserable fourth inning.

AMERICAN LEAGUE

WHITE SOX 6, TWINS 1:

Jim Thome hit a two-run homer in the sixth inning to break open a pitcher's duel and Mark Buehrle was dominant into the seventh inning as host Chicago won the last two of the three-game series with Minnesota. Buehrle (1-0) gave up Delmon Young's homer in the second and then retired 15 straight batters before being pulled with one out in the seventh.

INDIANS 8, BLUE JAYS 4:

Anthony Reyes pitched six innings, allowing four runs, and host Cleveland got its first victory of the season by beating Toronto in the final of a three-game series. Travis Hafner and Mark DeRosa each hit a two-run homer for the Indians.

RAYS 11, ORIOLES 3:

James Shields (1-1) pitched seven innings of three-hit ball, Evan Longoria hit his major league-leading fifth home run and Tampa Bay averted a three-game sweep by beating host Baltimore. Ben Zobrist, Jason Bartlett and Carlos Pena also homered for the Rays.

MARINERS 1, ATHLETICS 0:

Erik Bedard allowed three hits pitching into the ninth inning and Mike Sweeney doubled in a run in the seventh as Seattle swept a three-game series at Oakland. Bedard (1-0) was within two outs of his second career shutout when he was lifted for David Aardsma, who struck out Jason Giambi and got Jack Cust to line out with a pair of runners aboard for his second save.

ROYALS 6, YANKEES 4:

John Buck homered and drove in three runs, helping host Kansas City rally to avoid a three-game sweep by New York. The Royals scored three runs with two outs in the eighth inning off Jose Veras and Phil Coke (0-1) to take a 4-3 lead.

TIGERS 6, RANGERS 4:

Brandon Inge homered and hit a two-run single in a six-run eighth inning as host Detroit completed a three-game sweep of Texas. Josh Hamilton and Ian Kinsler hit two-run homers for Texas.